The National League defeated the American League 5-1 in the 2011 MLB All-Star Game. With the win, the National League will have home field advantage in the World Series for the second consecutive season.

After Adrian Gonzalez of the Boston Red Sox hit a solo home run to put the AL up 1-0, the AL All-Stars were shut down. Prince Fielder of the Milwaukee Brewers put the NL up 3-1 with a 3-run blast off of Texas Rangers pitcher C.J. Wilson. The NL would go on to win 5-1. Prince Fielder was named the All-Star game MVP.